Performing whole genome SNP analysis with mapping performed on the external calculation engine

In this tutorial all steps needed to perform a wgSNP analysis in BioNumerics are illustrated using the whole genome demonstration database of Staphylococcus aureus.

wgSNP analysis

Whole-genome Single Nucleotide Polymorphism (SNP) analysis using BioNumerics. See the wgSNP application page for a complete overview.
Download PDF file: 
Download demonstration database: 
WGS demo database for Staphylococcus aureus

Demonstration database containing data for a set of 97 Staphylococcus aureus isolates originating from three published studies. This database uses publicly available next-generation sequence reads from the Sequence Read Archive (SRA). For each isolate, NGS reads were de novo assembled into genome sequences. wgMLST alleles were called using the assembly-based and assembly-free method.

Note that the downloaded database backup file (.bnbk) can be restored via the Restore database... functionality in the BioNumerics startup screen.

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