BioNumerics version 6.1 released

Ten months after the impressive major upgrade to BioNumerics version 6.0, Applied Maths proudly presents BioNumerics version 6.1 (see also the Press release). Honoring a good old Applied Maths tradition of supplying its “minor” upgrades with a list of new features worth the label “major”, we have provided an great number of novel and improved features in this upgrade, covering many aspects of databasing, analysis and the user interface.

In view of the ongoing process of integrating Kodon into BioNumerics, a new module Chromosome comparison is launched, featuring the Comparative Chromosome Mapping tools of Kodon. This module offers side-by-side comparison of genomes and chromosomes, analysis of organization and functional behavior of genomes, alignment of multiple chromosomes, chromosome-based SNP analysis, and dNdS analysis.

In addition, BioNumerics version 6.1 comes with 4 new plugins:

• MIRU-VNTR plugin: is based on the successful MLVA plugin and provides specific functionality for Mycobacterium interspersed repetitive units typing. The plugin synchronizes with the MIRU-VNTRplus server and allows types to be assigned automatically and new types to be assigned.
• SNP genotyping plugin: automated and reliable SNP calling and genotyping of TaqMan® based SNP genotyping technology such as Applied Biosystems 7900HT, BMG Labtech 384-well microplate readers, and the Fluidigm Dynamic Array system.
• Diversilab plugin: import and analysis of patterns generated using the Diversilab™ system from bioMérieux. BioNumerics stores the patterns as fingerprints in a database and provides smart on-the-fly normalization algorithms for automatically aligning the Diversilab patterns within a comparison.
• User management plugin: provides easy export and import of groups of users and is particularly useful in multi-user environments.